STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pthpeptidyl-tRNA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)    
Predicted Functional Partners:
ychF
GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.925
mfd
Transcription-repair coupling factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.904
PriA
Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.796
tilS
tRNA(Ile)-lysidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.772
prfA
Peptide chain release factor 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.675
PrfB
Peptide chain release factor 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.624
divIC
Septum formation initiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.617
polA
DNA polymerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.564
guaA
GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.561
gatC_2
glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
  
 
  0.558
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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