STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ulaDCatalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)    
Predicted Functional Partners:
AKZ49721.1
Xylulose 5-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
AKZ49724.1
Ascorbate 6-phosphate lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.985
araD
Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.969
ulaC_2
PTS system ascorbate-specific transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; functions with enzymes IIB (sgaB; ulaB) and IIC (sgaT; ulaA) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.968
ulaB_2
PTS system ascorbate-specific transporter subunit IIB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; functions with enzymes IIC (sgaT; ulaA) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.869
AKZ49717.1
PTS system ascorbate-specific transporter subunit IIC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.865
MalF
Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.833
nanE
N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
  
    0.801
AKZ49723.1
Ascorbate 6-phosphate lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.472
AKZ50064.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.471
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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