STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mecAAdapter protein mecA; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)    
Predicted Functional Partners:
ClpC
Clp protease ClpX; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.935
Pbp2A
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.879
NorA
Multidrug MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.823
wecA
UDP-N-acetylglucosamine:UDP-P N-acetylglucosaminyl-1-P transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.806
ClpE
Clp protease ClpX; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.766
ezrA
Septation ring formation regulator EzrA; Acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.744
cypB
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
    0.738
AKZ49667.1
Adenine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.731
AKZ49946.1
Multidrug ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.704
clpP
Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.697
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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