STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mscSMechanosensitive ion channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)    
Predicted Functional Partners:
mscL
Large-conductance mechanosensitive channel; Homopentamer; channel that opens in response to pressure or hypoosmotic shock; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.888
ktrA
Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.797
GlpF2
Glycerol ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.656
nupX
Na+ dependent nucleoside transporter domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.581
pstB
Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
    
 0.564
trpS
tryptophan--tRNA ligase; Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.526
ProA
Gamma-glutamyl phosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.498
ProC
Pyrroline-5-carboxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.469
pstB3
Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
    
 0.465
OpuABC
Glycine/betaine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.458
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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