STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RecDExodeoxyribonuclease V subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (817 aa)    
Predicted Functional Partners:
recJ
Single-stranded DNA exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.853
recO
DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination.
   
  
 0.789
recR
Recombinase; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
  
 0.786
recG
ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.770
ruvB
ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
   
  
 0.708
recX
Recombination regulator RecX; Binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.705
ruvA
ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
     
 0.698
AKZ49860.1
Ribonuclease HIII; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.681
lepB-2
Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
  
    0.653
recN
DNA recombination protein RecN; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.630
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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