STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKZ49905.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)    
Predicted Functional Partners:
BcaT
Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.918
ldh
Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.899
AcpS
Alanine racemase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.836
AKZ50966.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.742
AKZ50232.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.717
AKZ49904.1
Universal stress protein UspA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.552
codY
Transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
     
 0.538
pabB
Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.519
gap
Glyceraldehyde-3-phosphate dehydrogenase; Also binds human plasminogen.
  
 
 0.510
lpdA
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.438
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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