Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fabF3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)    
Predicted Functional Partners:
FabH
3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
fabD
ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
fabG-2
3-ketoacyl-ACP reductase; Catalyzes the formation of 3-hydroxybutyryl-CoA from acetoacetyl-CoA in polyhydroxyalkanoate synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
fabZ
hydroxymyristoyl-ACP dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.999
fabK
2-nitropropane dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
acpP-2
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
 
 
 0.997
AccC
acetyl-CoA carboxylase; An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.996
AccB
acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
  
 0.990
fabG
3-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.989
AccA
acetyl-CoA carboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.988
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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