STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKZ49942.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)    
Predicted Functional Partners:
tsaE
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.821
AKZ49941.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.781
recF
Recombinase RecF; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.568
AKZ50883.1
Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
  
     0.524
AKZ49992.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.495
whiA
Sporulation protein; Involved in cell division and chromosome segregation.
  
     0.478
wecA
UDP-N-acetylglucosamine:UDP-P N-acetylglucosaminyl-1-P transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.474
AKZ49939.1
Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.472
codY
Transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
  
   
 0.466
AKZ50678.1
Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.449
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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