STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ethRTetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.611
atpE
ATP F0F1 synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
      
 0.557
AKZ49971.1
DegV domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.482
yheD
Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.459
yidA_1
Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.459
AKZ50942.1
Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.459
AKZ50432.1
Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.453
rsmG
16S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.436
rpoB
DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.424
AKZ49791.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.416
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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