STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKZ49988.13-dehydroquinate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)    
Predicted Functional Partners:
ProB
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.945
AKZ51355.1
Macrolide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
0.907
lolD_2
Macrolide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
0.893
AKZ49987.1
Enterocin immunity protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.664
proB
Gamma-glutamyl kinase; Catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.605
ProA
Gamma-glutamyl phosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.585
pstB
Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
   
0.498
atpD-2
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
   
 
 0.439
tkt
Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.438
atpG
ATP synthase F0F1 subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
   
   0.431
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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