STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsLCell division protein FtsL; Essential cell division protein; Belongs to the FtsL family. (107 aa)    
Predicted Functional Partners:
rsmH
16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
  
  
 0.968
divIC
Septum formation initiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.952
DivIB
Cell division protein FtsQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.926
AKZ49992.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.912
FtsW
Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
  
  
 0.858
AKZ49993.1
phospho-N-acetylmuramoyl-pentapeptide- transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.850
ezrA
Septation ring formation regulator EzrA; Acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.786
Pbp1b
Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.766
yvqC
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.742
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
     
 0.729
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.