Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKZ49992.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (751 aa)    
Predicted Functional Partners:
Pbp1A
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.996
Pbp2A
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.991
FtsW
Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
 
 
 0.988
Pbp1b
Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.979
AKZ49993.1
phospho-N-acetylmuramoyl-pentapeptide- transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.976
ftsL
Cell division protein FtsL; Essential cell division protein; Belongs to the FtsL family.
  
 
 0.962
DivIB
Cell division protein FtsQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.962
DacA2
Peptidase M15; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.959
rsmH
16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
 
  
 0.951
DacA1
D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.937
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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