STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKZ49994.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)    
Predicted Functional Partners:
rsmH
16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
  
  
 0.719
pnp
Polynucleotide phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.716
ftsL
Cell division protein FtsL; Essential cell division protein; Belongs to the FtsL family.
       0.711
AKZ49992.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.711
AKZ49993.1
phospho-N-acetylmuramoyl-pentapeptide- transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.711
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.676
cypB
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
 
 0.647
AapA
Amino acid ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.632
rnr
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.599
yqeH
GTPase; In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.599
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.