Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
AKZ49999.1Amino acid transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)    
Predicted Functional Partners:
trxB
Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.707
NadE
Nicotinate phosphoribosyltransferase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.703
nadE
NAD synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.680
AKZ49596.1
Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.563
AapA
Amino acid ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.554
AKZ49996.1
Amino acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.422
AKZ49995.1
Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.413
AKZ51257.1
Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.413
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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