STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepCDerived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)    
Predicted Functional Partners:
PepXP
X-prolyl-dipeptidyl aminopeptidase; Catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.883
pcp
Pyrrolidone-carboxylate peptidase; Catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.865
nadE
NAD synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.768
PepN
Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.753
pepT
Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.740
pepA
Glutamyl aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.706
PepQ
Dipeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.700
nusA
Transcription elongation factor NusA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.683
alaS
alanine--tRNA ligase; Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.647
NadE
Nicotinate phosphoribosyltransferase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.518
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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