Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
yvqEHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)    
Predicted Functional Partners:
yvqC
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
YvqF
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.964
salR
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.894
AKZ50026.1
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.806
yabR
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.805
pknB
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.759
SagH
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.732
pppL
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.731
rsmB
16S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.714
AKZ50019.1
methionyl-tRNA formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.689
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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