STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mscLLarge-conductance mechanosensitive channel; Homopentamer; channel that opens in response to pressure or hypoosmotic shock; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)    
Predicted Functional Partners:
mscS
Mechanosensitive ion channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.888
rpoD
RNA polymerase sigma factor RpoD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.673
ktrA
Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.617
MetK2
Catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.595
dnaG
DNA primase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.584
GlpF2
Glycerol ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.580
ProC
Pyrroline-5-carboxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.548
polA
DNA polymerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.489
ybeY
Metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
      
 0.481
CutC
Copper homeostasis protein CutC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.465
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.