Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
rfbDdTDP-4-dehydrorhamnose reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)    
Predicted Functional Partners:
CpsFP
dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 0.998
rfbB
dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 0.998
RgpAc
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.909
RgpBc
alpha-L-Rha alpha-1,3-L-rhamnosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.888
wecA
UDP-N-acetylglucosamine:UDP-P N-acetylglucosaminyl-1-P transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.841
RgpFc
alpha-L-Rha alpha-1,3-L-rhamnosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.822
DexB
Glucan 1,6-alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.811
RgpCc
Glycosyl transferase family 9; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.760
rgpDc
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.760
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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