STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apbA2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (307 aa)    
Predicted Functional Partners:
AKZ50156.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.937
FruA
PTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.565
folE
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.537
TrxB
ferredoxin-NADP reductase; Catalyzes the oxidation of ferredoxin with NADP; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.511
trmD
tRNA (guanine-N1)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
FruR
DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.497
rimM
16S rRNA processing protein RimM; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.493
pfkB
Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.483
pepT
Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.474
pepV
Dipeptidase PepV; Divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.455
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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