STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKZ50174.1GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)    
Predicted Functional Partners:
SptS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.965
sptR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     0.950
yjbM
GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.923
RelA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.919
nrdD
Ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
folE
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
mnmE
tRNA modification GTPase MnmE; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.564
AKZ50166.1
Nucleoside diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.500
dgkA
UDP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.500
AKZ50173.1
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.479
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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