STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKZ50280.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (64 aa)    
Predicted Functional Partners:
AKZ50281.1
Relaxase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
      0.899
addA
ATP-dependent helicase/nuclease subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.575
AKZ50279.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.567
dnaN
DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.557
topA
DNA topoisomerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.478
pcrA
ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.441
polA
DNA polymerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.430
AKZ50734.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.428
AKZ50865.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.428
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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