STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKZ50318.1Gamma-glutamyl hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)    
Predicted Functional Partners:
FolC1
Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.835
FolC2
Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.834
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.819
rex
Rex family transcripional regulator; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.799
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HPPK family.
     
 0.651
AKZ51082.1
Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.608
folE
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.595
glnA
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.537
NifS2
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.502
AKZ50320.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.491
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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