STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SatDDNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)    
Predicted Functional Partners:
SatE
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.958
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.700
rpoB
DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.676
RpoA
DNA-directed RNA polymerase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.608
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.608
pknB
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.600
topA
DNA topoisomerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.596
Gid
tRNA (uracil-5-)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.538
Ddh
Lactate dehydrogenase; Catalyzes the formation of pyruvate from lactate; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.519
AKZ51302.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.500
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.