Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKZ51363.1Citrate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)    
Predicted Functional Partners:
CitG
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.858
citG_2
2-(5'-triphosphoribosyl)-3'-dephospho CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.767
AKZ50371.1
acetyl-CoA carboxylase; Composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.636
AKZ50370.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.592
oadB
glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
 
     0.432
citF
citrate-ACP transferase, the alpha subunit catalyzes the formation of (3S)-citryl-CoA from acetyl-CoA and citrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.427
citD
Citrate lyase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.425
citX
ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.420
DpiB
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.405
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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