Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
xerSSite-specific tyrosine recombinase XerS; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. (356 aa)    
Predicted Functional Partners:
FtsK
Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.865
pcrA
ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.761
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.746
recF
Recombinase RecF; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.731
rpsI
30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family.
    
 
 0.639
rpmG
50S ribosomal protein L33; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL33 family.
    
 
 0.599
recN
DNA recombination protein RecN; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.581
xerD
Recombinase XerD; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.577
guaA
GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.550
sstT
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.549
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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