STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arlRTranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)    
Predicted Functional Partners:
ciaH
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
vicK
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.967
Ihk
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.963
csrS
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.954
HtrA
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.948
SptS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.921
SrtK
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.769
AKZ50802.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.647
mgrA
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.634
AKZ51131.1
SalK; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.608
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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