Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKZ50426.1Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)    
Predicted Functional Partners:
AKZ50423.1
RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.872
AKZ50424.1
Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.868
AKZ50425.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0223 family.
       0.868
RpoA
DNA-directed RNA polymerase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.847
MreA
Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.802
truB
tRNA pseudouridine synthase B; Catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.782
AKZ50045.1
Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.754
pstS
Phosphate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.740
pstA
Phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.709
pstC
Phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.709
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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