STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKZ50461.1Pyrogenic exotoxin SpeK; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)    
Predicted Functional Partners:
AKZ49667.1
Adenine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.821
AKZ50698.1
Pyrogenic exotoxin SpeK; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  
0.800
AKZ50279.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.741
AKZ50488.1
HNH nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.580
AKZ50853.1
HNH nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.579
AKZ50460.1
Exotoxin M precursor; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
0.412
AKZ50596.1
DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.406
AKZ50462.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.401
AKZ50463.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.401
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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