STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)    
Predicted Functional Partners:
aroC
Catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
AroK
Shikimate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
AroB
3-dehydroquinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.975
aroE_2
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
 0.965
Cmk
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.926
AKZ50819.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.731
AroE2
Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.695
Map
Methionine aminopeptidase; Catalyzes the removal of N-terminal amino acids from peptides and arylamides; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.612
AKZ50623.1
Ribonuclease BN; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.587
PheT
phenylalanyl-tRNA synthase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.575
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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