STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKZ50637.12-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)    
Predicted Functional Partners:
KgdA
Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.989
AKZ50634.1
2-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.985
AKZ50894.1
2-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.917
AKZ50632.1
Mannonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.912
Rpe
Ribulose-phosphate 3-epimerase; Catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.882
AKZ50636.1
Beta-glucuronidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.757
AKZ50633.1
Glucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.678
AKZ50638.1
Glucuronide permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.656
AKZ50635.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.613
GabD
Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.585
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.