STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKZ50827.1DNAse; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)    
Predicted Functional Partners:
AKZ50074.1
Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.863
SmeZ
Exosortase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.680
AKZ50968.1
Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.590
ska
Kinase; This protein is not a protease, but it activates plasminogen by complexing with it. As a potential virulence factor, it is thought to prevent the formation of effective fibrin barriers around the site of infection, thereby contributing to the invasiveness of the cells (By similarity).
      
 0.557
ComEC
Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.466
dnaseB
Mitogenic factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
0.436
PepD
Peptidase C69; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.400
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.