STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AspCAspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)    
Predicted Functional Partners:
AsnB
Asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.916
AsnA
Asparagine synthetase AsnA; Catalyzes the formation of asparagine from aspartate and ammonia; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.903
ldh
Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.901
AKZ50232.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.771
asnC
asparagine--tRNA ligase; Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.758
AKZ50966.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.727
MurF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.535
DinG
ATP-dependent DNA helicase; Unwinds DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.531
pabB
Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.519
gap
Glyceraldehyde-3-phosphate dehydrogenase; Also binds human plasminogen.
  
 
 0.512
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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