STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
queGEpoxyqueuosine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)    
Predicted Functional Partners:
queA
S-adenosylmethionine tRNA ribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.969
folE
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.851
yeeN
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.821
tgt
Queuine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.610
PrfB
Peptide chain release factor 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.557
trmD
tRNA (guanine-N1)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.544
FtsX
Cell division protein FtsX; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
  
    0.488
ftsE
Cell division protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
  
    0.487
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.