Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
amiD_1N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)    
Predicted Functional Partners:
thiT
Thiamine transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.682
AKZ50915.1
Additional lipoprotein component of cobalamin ECF transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.661
AKZ50919.1
prolyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
       0.627
AKZ51298.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.619
AKZ49607.1
Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.614
AKZ50920.1
Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.571
AKZ50058.1
DNA gyrase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.544
FtsW
Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
       0.483
Ppc
Phosphoenolpyruvate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.483
lysS
lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.467
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
Server load: low (10%) [HD]