STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKZ50928.1General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)    
Predicted Functional Partners:
AKZ50927.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.871
rpoE
DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
  
     0.750
Lgt
Prolipoprotein diacylglyceryl transferase; Transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.747
PtsK
Serine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.747
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
     0.643
ezrA
Septation ring formation regulator EzrA; Acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.616
AKZ49946.1
Multidrug ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.560
AKZ51106.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.547
AKZ50426.1
Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.546
AKZ50320.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.520
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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