STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MefEMacrolide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)    
Predicted Functional Partners:
stcA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.825
AKZ50961.1
UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.705
msrB-2
Peptide methionine sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.646
rlmN
Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
   
  
 0.599
AKZ50443.1
Sodium:alanine symporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.597
msrA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.585
NorA
Multidrug MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.564
rplV
50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
   
  
 0.562
msrC
GAF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.538
AKZ50962.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.505
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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