Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yozEHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0346 family. (71 aa)    
Predicted Functional Partners:
msrA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.819
AKZ51021.1
S1 RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.767
AKZ50782.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.694
AKZ50749.1
GDSL family lipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.674
frr
Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
       0.671
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
       0.652
mecA
Adapter protein mecA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.623
PhoH
Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.621
AKZ50748.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.590
AKZ50232.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.563
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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