Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lctOLactate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)    
Predicted Functional Partners:
Nox
NADH oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.755
ldh
Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
  
 0.709
ccpA
Catabolite control protein A; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.662
AKZ51057.1
dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.543
cepA
Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.542
glpO
Alpha-glycerophosphate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.510
xth
Exodeoxyribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.504
eutD
Phosphotransacetylase; In Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.484
sodA
Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
   
  
 0.477
PgmA
Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.474
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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