STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)    
Predicted Functional Partners:
cysE
Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.998
mrnC
Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.
  
  
 0.974
cysK
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.931
rlmB
rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.865
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
  
 0.819
SerS
serine--tRNA ligase; Catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.804
AKZ51154.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.794
GltX
glutamyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.724
AKZ51159.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.689
LeuS
leucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.684
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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