STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mgrAMarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)    
Predicted Functional Partners:
rlmH
SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.820
NorA
Multidrug MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.663
arlR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.634
AKZ51017.1
Myosin-cross-reactive antigen; In group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.628
polC
DNA polymerase III PolC; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
     
 0.587
AKZ49975.1
2,5-diketo-D-gluconic acid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.565
AKZ51171.1
NADPH-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.554
AKZ50331.1
Glycine/betaine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.547
RegR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.443
AKZ50825.1
Zinc-binding protein AdcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.422
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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