Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKZ51257.1Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)    
Predicted Functional Partners:
hutH
Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.775
AKZ51256.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.568
HutG
Formimidoylglutamase; Catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.544
AmyA
Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.469
AmyB
Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.469
DexB
Glucan 1,6-alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.469
treC
Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.469
Fhs2
Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.446
AKZ51254.1
Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.423
ftcD
Glutamate formiminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.417
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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