NRF1 protein (Melopsittacus undulatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NRF1

Nuclear respiratory factor 1. (512 aa)

Predicted Functional Partners:

PPARGC1A

0.941

ENSMUNP00000011344

0.861

PPARGC1B

0.824

RBM22

0.803

LOC101867666

0.687

SIRT1

0.569

GABPA

0.536

SIRT7

0.531

ENSMUNP00000018513

0.519

LOC101870620

0.504

Your Current Organism:

Melopsittacus undulatus

NCBI taxonomy Id: 13146
Other names: M. undulatus, Melopsittacus unduratus, budgerigar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMUNP00000011344	GABPA	ENSMUNP00000011344	ENSMUNP00000006857	annotation not available	GA binding protein transcription factor subunit alpha.	0.493
ENSMUNP00000011344	LOC101867666	ENSMUNP00000011344	ENSMUNP00000014992	annotation not available	Transcription factor A, mitochondrial.	0.667
ENSMUNP00000011344	NRF1	ENSMUNP00000011344	ENSMUNP00000001730	annotation not available	Nuclear respiratory factor 1.	0.861
ENSMUNP00000011344	SIRT1	ENSMUNP00000011344	ENSMUNP00000010624	annotation not available	Sirtuin 1.	0.858
ENSMUNP00000011344	SIRT7	ENSMUNP00000011344	ENSMUNP00000012398	annotation not available	Sirtuin 7.	0.704
ENSMUNP00000018513	LOC101867666	ENSMUNP00000018513	ENSMUNP00000014992	annotation not available	Transcription factor A, mitochondrial.	0.525
ENSMUNP00000018513	LOC101870620	ENSMUNP00000018513	ENSMUNP00000009956	annotation not available	Cytochrome c-like.	0.491
ENSMUNP00000018513	NRF1	ENSMUNP00000018513	ENSMUNP00000001730	annotation not available	Nuclear respiratory factor 1.	0.519
GABPA	ENSMUNP00000011344	ENSMUNP00000006857	ENSMUNP00000011344	GA binding protein transcription factor subunit alpha.	annotation not available	0.493
GABPA	LOC101867666	ENSMUNP00000006857	ENSMUNP00000014992	GA binding protein transcription factor subunit alpha.	Transcription factor A, mitochondrial.	0.665
GABPA	NRF1	ENSMUNP00000006857	ENSMUNP00000001730	GA binding protein transcription factor subunit alpha.	Nuclear respiratory factor 1.	0.536
GABPA	PPARGC1A	ENSMUNP00000006857	ENSMUNP00000021277	GA binding protein transcription factor subunit alpha.	PPARG coactivator 1 alpha.	0.521
LOC101867666	ENSMUNP00000011344	ENSMUNP00000014992	ENSMUNP00000011344	Transcription factor A, mitochondrial.	annotation not available	0.667
LOC101867666	ENSMUNP00000018513	ENSMUNP00000014992	ENSMUNP00000018513	Transcription factor A, mitochondrial.	annotation not available	0.525
LOC101867666	GABPA	ENSMUNP00000014992	ENSMUNP00000006857	Transcription factor A, mitochondrial.	GA binding protein transcription factor subunit alpha.	0.665
LOC101867666	LOC101870620	ENSMUNP00000014992	ENSMUNP00000009956	Transcription factor A, mitochondrial.	Cytochrome c-like.	0.408
LOC101867666	NRF1	ENSMUNP00000014992	ENSMUNP00000001730	Transcription factor A, mitochondrial.	Nuclear respiratory factor 1.	0.687
LOC101867666	PPARGC1A	ENSMUNP00000014992	ENSMUNP00000021277	Transcription factor A, mitochondrial.	PPARG coactivator 1 alpha.	0.916
LOC101867666	RBM22	ENSMUNP00000014992	ENSMUNP00000002620	Transcription factor A, mitochondrial.	RNA binding motif protein 22.	0.405
LOC101867666	SIRT1	ENSMUNP00000014992	ENSMUNP00000010624	Transcription factor A, mitochondrial.	Sirtuin 1.	0.643