STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4793 aa)    
Predicted Functional Partners:
RNF8
Ring finger protein 8.
   
 0.837
RANBP2
E3 SUMO-protein ligase RanBP2.
   
 0.725
BRCA1
BRCA1 DNA repair associated.
    
 0.712
LOC101878836
Ubiquitin conjugating enzyme E2 N.
    
  0.698
PIAS4
Protein inhibitor of activated STAT 4.
    
 0.690
ZFAND4
Zinc finger AN1-type containing 4.
    
 0.690
UBE3A
Ubiquitin protein ligase E3A.
   
0.682
BARD1
BRCA1 associated RING domain 1.
    
 0.671
UBE2I
Ubiquitin conjugating enzyme E2 I.
    
  0.661
RNF168
Ring finger protein 168.
    
 0.656
Your Current Organism:
Melopsittacus undulatus
NCBI taxonomy Id: 13146
Other names: M. undulatus, Melopsittacus unduratus, budgerigar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.