STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIX3SIX homeobox 3. (300 aa)    
Predicted Functional Partners:
EYA4
EYA transcriptional coactivator and phosphatase 4.
   
 
 0.674
EYA1
EYA transcriptional coactivator and phosphatase 1.
   
 
 0.674
EYA2
EYA transcriptional coactivator and phosphatase 2.
   
 
 0.674
EYA3
EYA transcriptional coactivator and phosphatase 3.
   
 
 0.674
PAX4
Paired box 4.
  
 
 0.531
VSX2
Visual system homeobox 2.
   
  
 0.480
OTX2
Orthodenticle homeobox 2.
   
 
 0.473
DLX1
Distal-less homeobox 1.
   
  
 0.466
PAX6
Paired box 6.
   
 
 0.456
TLE5
TLE family member 5, transcriptional modulator.
    
 
 0.435
Your Current Organism:
Melopsittacus undulatus
NCBI taxonomy Id: 13146
Other names: M. undulatus, Melopsittacus unduratus, budgerigar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.