STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHEK1Checkpoint kinase 1. (476 aa)    
Predicted Functional Partners:
ATR
ATR serine/threonine kinase.
    
 0.996
WRN
WRN RecQ like helicase.
   
 0.995
CDC25A
Cell division cycle 25A.
   
 0.995
CHEK2
Checkpoint kinase 2.
   
0.994
CLSPN
Claspin.
   
 0.992
MCM4
Minichromosome maintenance complex component 4.
   
 0.986
CDC45
Cell division cycle 45.
   
 0.980
TP53BP1
Tumor protein p53 binding protein 1.
    
 
 0.976
RAD51
RAD51 recombinase.
   
 0.973
EXO1
Exonuclease 1.
   
 0.950
Your Current Organism:
Melopsittacus undulatus
NCBI taxonomy Id: 13146
Other names: M. undulatus, Melopsittacus unduratus, budgerigar
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