STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMGCR3-hydroxy-3-methylglutaryl-CoA reductase. (936 aa)    
Predicted Functional Partners:
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1.
  
 
 0.992
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2.
  
 
 0.990
UBIAD1
UbiA prenyltransferase domain containing 1.
   
 
 0.959
MVK
Mevalonate kinase.
  
 0.956
MVD
Mevalonate diphosphate decarboxylase.
  
 
 0.951
SQLE
Squalene epoxidase.
  
  
 0.919
CYP51A1
Lanosterol 14-alpha demethylase.
  
  
 0.912
AMFR
Autocrine motility factor receptor.
   
 
 0.904
INSIG2
Insulin induced gene 2.
   
 
 0.874
INSIG1
Insulin induced gene 1.
   
 
 0.874
Your Current Organism:
Melopsittacus undulatus
NCBI taxonomy Id: 13146
Other names: M. undulatus, Melopsittacus unduratus, budgerigar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.