STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A3N2PX91Ribonuclease H-like protein. (567 aa)    
Predicted Functional Partners:
A0A3N2PKQ0
Uncharacterized protein.
  
 0.999
A0A3N2PMP5
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.999
A0A3N2PSW5
Phosphatidylinositol 3; Belongs to the PI3/PI4-kinase family.
   
 0.999
A0A3N2PT74
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.999
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.999
A0A3N2Q3B5
Uncharacterized protein.
   
 0.999
A0A3N2Q4X0
Replication protein A, subunit RPA32.
   
 0.999
A0A3N2PL69
DNA repair exonuclease; Belongs to the MRE11/RAD32 family.
  
 0.998
A0A3N2PLI7
Uncharacterized protein.
   
 0.998
A0A3N2PMK0
Exodeoxyribonuclease.
  
 0.998
Your Current Organism:
Sodiomyces alkalinus
NCBI taxonomy Id: 1314773
Other names: Plectosphaerellaceae sp. AGG-2013 F11, S. alkalinus F11, Sodiomyces alkalinus F11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.