STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A166BPD4DHS-like NAD/FAD-binding domain-containing protein. (352 aa)    
Predicted Functional Partners:
A0A166J705
NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.
  
 
0.847
A0A166GH25
DHS-like NAD/FAD-binding domain-containing protein.
  
 
0.790
A0A166HZX6
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.777
A0A166IKN1
Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.
   
 0.769
A0A166HZV6
SIR2-domain-containing protein.
  
 
0.762
A0A166BRV7
NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
  
  
0.750
A0A166CRS6
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.743
A0A166FN81
Uncharacterized protein.
   
 0.741
A0A166IEY5
ATP-NAD kinase.
  
 
 0.718
A0A166J484
Nudix hydrolase domain-containing protein.
    
 0.709
Your Current Organism:
Sistotremastrum suecicum
NCBI taxonomy Id: 1314776
Other names: S. suecicum HHB10207 ss-3, Sistotremastrum suecicum HHB10207 ss-3
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