node1 | node2 | node1 annotation | node2 annotation | score |
A0A166BPD4 | A0A166BRV7 | DHS-like NAD/FAD-binding domain-containing protein. | NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | 0.750 |
A0A166BPD4 | A0A166CRS6 | DHS-like NAD/FAD-binding domain-containing protein. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.743 |
A0A166BPD4 | A0A166FN81 | DHS-like NAD/FAD-binding domain-containing protein. | Uncharacterized protein. | 0.741 |
A0A166BPD4 | A0A166GH25 | DHS-like NAD/FAD-binding domain-containing protein. | DHS-like NAD/FAD-binding domain-containing protein. | 0.790 |
A0A166BPD4 | A0A166HZV6 | DHS-like NAD/FAD-binding domain-containing protein. | SIR2-domain-containing protein. | 0.762 |
A0A166BPD4 | A0A166HZX6 | DHS-like NAD/FAD-binding domain-containing protein. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.777 |
A0A166BPD4 | A0A166IEY5 | DHS-like NAD/FAD-binding domain-containing protein. | ATP-NAD kinase. | 0.718 |
A0A166BPD4 | A0A166IKN1 | DHS-like NAD/FAD-binding domain-containing protein. | Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. | 0.769 |
A0A166BPD4 | A0A166J484 | DHS-like NAD/FAD-binding domain-containing protein. | Nudix hydrolase domain-containing protein. | 0.709 |
A0A166BPD4 | A0A166J705 | DHS-like NAD/FAD-binding domain-containing protein. | NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. | 0.847 |
A0A166BRV7 | A0A166BPD4 | NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | DHS-like NAD/FAD-binding domain-containing protein. | 0.750 |
A0A166BRV7 | A0A166CRS6 | NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.801 |
A0A166BRV7 | A0A166FN81 | NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | Uncharacterized protein. | 0.741 |
A0A166BRV7 | A0A166GH25 | NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | DHS-like NAD/FAD-binding domain-containing protein. | 0.848 |
A0A166BRV7 | A0A166HZV6 | NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | SIR2-domain-containing protein. | 0.800 |
A0A166BRV7 | A0A166HZX6 | NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.777 |
A0A166BRV7 | A0A166IEY5 | NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | ATP-NAD kinase. | 0.781 |
A0A166BRV7 | A0A166IKN1 | NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. | 0.821 |
A0A166BRV7 | A0A166J484 | NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | Nudix hydrolase domain-containing protein. | 0.775 |
A0A166BRV7 | A0A166J705 | NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. | 0.908 |