STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A166C1C3Uncharacterized protein. (518 aa)    
Predicted Functional Partners:
A0A166CWZ3
DNA polymerase.
   
 0.998
A0A165ZTH8
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.996
A0A166G5Z1
Uncharacterized protein.
   
 0.996
A0A166J4K4
DNA polymerase.
   
 0.989
A0A166AEF0
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.971
A0A166HXG3
DNA polymerase.
   
 0.969
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.968
A0A166JCC8
Mitotic spindle checkpoint HORMA domain-containing protein.
    
 
 0.949
A0A166IU16
DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.
  
 
 0.932
A0A166FI23
DNA polymerase alpha, subunit B.
   
 0.906
Your Current Organism:
Sistotremastrum suecicum
NCBI taxonomy Id: 1314776
Other names: S. suecicum HHB10207 ss-3, Sistotremastrum suecicum HHB10207 ss-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.