A0A165MRC8 protein (Exidia glandulosa) - STRING interaction network

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second shell of interactors

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filled nodes:
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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

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Score

A0A165MRC8

Voltage-gated potassium channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (792 aa)

Predicted Functional Partners:

A0A165G9R5

0.607

A0A165ZLM4

0.607

A0A165FTR1

0.487

A0A165FWL6

0.487

A0A165M556

0.487

A0A165MZA7

0.487

A0A166AL44

0.487

A0A165GSL6

0.453

A0A165GT96

0.453

A0A165LSY8

0.453

Your Current Organism:

Exidia glandulosa

NCBI taxonomy Id: 1314781
Other names: E. glandulosa HHB12029, Exidia glandulosa HHB12029

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A165FTR1	A0A165G9R5	Uncharacterized protein.	Uncharacterized protein.	0.539
A0A165FTR1	A0A165GSL6	Uncharacterized protein.	Alpha-L-arabinofuranosidase B domain protein.	0.585
A0A165FTR1	A0A165GT96	Uncharacterized protein.	Alpha-L-arabinofuranosidase B domain protein.	0.585
A0A165FTR1	A0A165LSY8	Uncharacterized protein.	Arabinosidase B.	0.585
A0A165FTR1	A0A165MRC8	Uncharacterized protein.	Voltage-gated potassium channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.487
A0A165FTR1	A0A165ZLM4	Uncharacterized protein.	Uncharacterized protein.	0.539
A0A165FWL6	A0A165G9R5	F-box domain-containing protein.	Uncharacterized protein.	0.539
A0A165FWL6	A0A165GSL6	F-box domain-containing protein.	Alpha-L-arabinofuranosidase B domain protein.	0.585
A0A165FWL6	A0A165GT96	F-box domain-containing protein.	Alpha-L-arabinofuranosidase B domain protein.	0.585
A0A165FWL6	A0A165LSY8	F-box domain-containing protein.	Arabinosidase B.	0.585
A0A165FWL6	A0A165MRC8	F-box domain-containing protein.	Voltage-gated potassium channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.487
A0A165FWL6	A0A165ZLM4	F-box domain-containing protein.	Uncharacterized protein.	0.539
A0A165G9R5	A0A165FTR1	Uncharacterized protein.	Uncharacterized protein.	0.539
A0A165G9R5	A0A165FWL6	Uncharacterized protein.	F-box domain-containing protein.	0.539
A0A165G9R5	A0A165GSL6	Uncharacterized protein.	Alpha-L-arabinofuranosidase B domain protein.	0.573
A0A165G9R5	A0A165GT96	Uncharacterized protein.	Alpha-L-arabinofuranosidase B domain protein.	0.573
A0A165G9R5	A0A165LSY8	Uncharacterized protein.	Arabinosidase B.	0.573
A0A165G9R5	A0A165M556	Uncharacterized protein.	Ribosomal protein L37; Binds to the 23S rRNA.	0.539
A0A165G9R5	A0A165MRC8	Uncharacterized protein.	Voltage-gated potassium channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.607
A0A165G9R5	A0A165MZA7	Uncharacterized protein.	Voltage-gated potassium channel.	0.745

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.818

expected number of edges:

22

PPI enrichment p-value:

0.0447

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006189

De novo IMP biosynthetic process

10 of 11

2.34

7.95

8.08e-19

GO:0006164

Purine nucleotide biosynthetic process

11 of 44

1.78

4.9

1.69e-17

GO:0006541

Glutamine metabolic process

2 of 14

1.54

0.71

0.0349

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004642

Phosphoribosylformylglycinamidine synthase activity

3 of 3

2.38

1.98

0.00019

GO:0016879

Ligase activity, forming carbon-nitrogen bonds

6 of 49

1.47

1.76

1.38e-05

GO:0016742

Hydroxymethyl-, formyl- and related transferase activity

2 of 4

2.08

1.06

0.0099

GO:0005524

ATP binding

7 of 303

0.75

0.52

0.0080

GO:0003824

Catalytic activity

11 of 1264

0.32

0.27

0.0114

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 940

0.41

0.3

0.0236

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:844

De novo IMP biosynthetic process

11 of 11

2.38

9.28

3.50e-22

CL:846

De novo IMP biosynthetic process

6 of 6

2.38

5.0

6.34e-11

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

11 of 93

1.46

2.98

1.98e-14

map01110

Biosynthesis of secondary metabolites

11 of 293

0.96

1.17

1.90e-09

map01100

Metabolic pathways

11 of 898

0.47

0.4

0.00024

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005829

Cytosol

8 of 298

0.81

0.7

0.00037

GOCC:0005737

Cytoplasm

11 of 647

0.61

0.54

4.23e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0658

Purine biosynthesis

11 of 16

2.22

8.21

1.86e-21

KW-0436

Ligase

7 of 84

1.3

1.69

1.09e-06

KW-0067

ATP-binding

7 of 253

0.83

0.68

0.0010

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02769

AIR synthase related protein, C-terminal domain

2 of 2

2.38

0.79

0.0357

PF00586

AIR synthase related protein, N-terminal domain

2 of 2

2.38

0.79

0.0357

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